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Webinar: Practical Calicivirus: All You Need to Know from Diagnosis to Adoption - 4/17/24

  • 1.  Webinar: Practical Calicivirus: All You Need to Know from Diagnosis to Adoption - 4/17/24

    Posted 03-01-2024 02:17 PM

    Feline calicivirus is a contagious, often severe virus in cats that can be difficult, time-consuming, and expensive to treat. However, standardized protocols help treat these cats efficiently, reduce transmission within the shelter, and get cats moving toward live outcomes. This webcast will cover diagnosing calicivirus without the use of expensive testing, treating the virus and caring for sick cats in the shelter, and clearing and adopting the cats after illness.

    This webcast was recorded on Wednesday, April 17, 2024 at 12n Pacific / 3p Eastern

    WATCH THE RECORDING

    Learning Objectives:

          Attendees will learn how to diagnose calicivirus without expensive testing.

          Attendees will take away best practice treatment protocols.

          Attendees will understand how, and when, to clear cats and move them along toward their outcome.

    This webinar will be recorded and has been pre-approved for 1.0 Certified Animal Welfare Administrator continuing education credits by The Association for Animal Welfare Advancement and by the National Animal Care & Control Association. It has also been approved for 1 hour of continuing education credit in jurisdictions which recognize RACE approval.

    Presenters:

    Monica Tarant and her black kitty


    @Monica Tarant
    Chief Innovation Officer, 
    Cincinnati Animal CARE and The Give Them Ten Movement

    A decade before anyone had heard of such a thing, Monica cut her teeth founding a trap-neuter-return organization in rural Illinois and pioneered one of the nation's first, and largest, working cat programs. In 2012, she joined Austin Pets Alive! where she led her team to an 88 percent growth in cat adoptions and helped Austin achieve a citywide 98 percent live release rate for cats. Monica then spent years as an instructor for the Maddie's Fund Lifesaving Academy teaching shelters best practices and innovative lifesaving programs, advancing research in feline retroviruses, and progressing public policy as a City of Austin Animal Advisory Commissioner. 

    Monica is a frequent speaker and advisor on innovative ways to save every cat, including cats with feline leukemia, community cats, and shelter cats in need of medical care.

    portrait of Jordana Moerbe


    @Jordana Moerbe
    Medical Care Director, Austin Pets Alive!

    Jordana brings over 15 years of experience in the animal welfare field and is one of the founding staff members of Austin Pets Alive!. Her work there created the Medical Triage and Wellness Clinic which is now the largest foster-centric medical clinic in the country and sees upwards of 7,500 medical cases each year. In 2017, her national work began in shelter clinic management, disease management, and outbreak response. Jordana worked with shelters and rescues nationwide to improve medical practices, live outcomes, and shelter efficiencies through innovative ideas and programming. She also served as the American Pets Alive Maddie's Medical Program Instructor, creating in-person training courses as well as online coursework.

    Jordana's passion continues to be shelter clinic management, outside-the-box thinking to industry problems, and helping people acquire realistic methods and tools to accomplish the job. She is a national conference speaker on these topics. Jordana resides just outside Austin with her husband, daughter, dogs, cats, and many farm animals.

     

    portrait of Lindsay


    Lindsay O'Gan
    Instructional Design Manager, Austin Pets Alive!

    Lindsay O'Gan started her career in the animal world as a vet tech at a private vet clinic in 2003. Seeing the shelter euthanasia crisis in Austin, she joined Dr. Ellen Jefferson at EmanciPet, a low-cost spay and neuter clinic. While working there, Lindsay helped quadruple their low-cost spay/neuter capacity through the creation of standing clinics in addition to their mobile hospital. 

    In 2008, it became clear that high volume spay/neuter was not solving the euthanasia crisis on its own, and Lindsay joined forces with Dr. Jefferson again, this time to start Austin Pets Alive's! life saving work. With a shoestring budget, Lindsay started APA's first vet clinic in an airstream trailer and began working with Dr. Jefferson to literally write the book on how to provide high quality, high volume medical care to shelter animals.  

    Lindsay helped build several programs at APA! over the years, including the cat rescue and foster program. Under Lindsay's leadership, the City of Austin became a no-kill city for cats for the first time ever in 2011, and has been no-kill for cats ever since. In 2012 she managed San Antonio Pets Alive's neonatal kitten nursery, working to find innovative solutions to saving one of the most vulnerable populations. 

    In 2015, Lindsay interrupted her animal career to get a bachelor's degree in Education from Texas State University, and became a Certified Science Teacher. Upon graduation, she worked as an 8th grade science teacher for 5 years in Wimberley, Texas. 

    In 2023, Lindsay returned to APA!, and brought her knowledge and passion for animal welfare, as well as experience and expertise in educational best practices, to create Austin Pets Alive's Training and Education Center!


    #Conferences,WorkshopsandWebcasts
    #EducationandTraining
    #Medicine,SurgeryandSterilization

    ------------------------------
    Alison Gibson
    Media Projects Manager
    Maddie's Fund
    ------------------------------



  • 2.  RE: Webinar: Practical Calicivirus: All You Need to Know from Diagnosis to Adoption - 4/17/24

    Posted 04-17-2024 01:21 PM

    Thank you to everyone who attended today's webcast on calicivirus! If you didn't have an opportunity to ask a question during the webcast, please let us know here and we'll do our best to get you an answer! 



    ------------------------------
    Monica Tarant
    Chief Innovation Officer
    The Give Them Ten Movement
    [givethemten.org]
    ------------------------------



  • 3.  RE: Webinar: Practical Calicivirus: All You Need to Know from Diagnosis to Adoption - 4/17/24

    Posted 05-15-2024 11:59 AM

    Thank you for a wonderful presentation.  Currently we have 3 cats that  have tested positive for caliciviris.  We have them quarantined in tower kennels, use gloves, gowns, booties when handling. They do not interact with any of our other cats at shelter. 

    One of the cats tested positive 12/21/2022, another 7/19/22. Each have had some teeth extractions and when they stop eating or have pain we take to vet for depo medrol/ convenia injection.  None of them have ever looked like the photos in the presentation. I'm just wondering if we are doing the right thing. It sounded like they technically only needed to be isolated for around 14 days once we see symptoms.  Looking for some guidance. 

    Thank you so much

    Mellisa from Colonial Capital Humane Society 



    ------------------------------
    Mellisa Gilham
    Cat Technician
    Colonial Capital Humane Society
    NC
    ------------------------------



  • 4.  RE: Webinar: Practical Calicivirus: All You Need to Know from Diagnosis to Adoption - 4/17/24

    Posted 05-16-2024 07:42 AM

    Hi Mellisa,

    Am I understanding correctly that you've had these two cats who tested positive for calicivirus for almost two years? 

    If they've had extractions and are on/off Depo, I assume they have stomatitis? If so, that should be addressed but the calici is long gone if ~2 years have passed.  IME, full mouth extractions (done correctly) +\- Depo yields the best long term success for stomatitis. But after this long in the shelter they really need to get out to foster which will immensely help with stress and recurring flare ups, too.  



    ------------------------------
    Monica Tarant
    Chief Innovation Officer
    The Give Them Ten Movement
    [givethemten.org]
    ------------------------------



  • 5.  RE: Webinar: Practical Calicivirus: All You Need to Know from Diagnosis to Adoption - 4/17/24

    Posted 05-20-2024 06:09 AM
    Hi Mellisa, 

    I agree with Monica. 

    What do you mean by "tested positive" for calici? What test was run?

    Have they been diagnosed with stomatitis? I'm assuming so based on the teeth extractions and depo injections. 

    It doesn't sound to me like these guys need quarantined after all of this time. Feel free to email if you'd like to continue the conversation - lindsay.ogan@austinpetsalive.org

    --
    Lindsay O'Gan
    Instructional Design Manager





  • 6.  RE: Webinar: Practical Calicivirus: All You Need to Know from Diagnosis to Adoption - 4/17/24

    Posted 06-29-2024 11:38 AM

    You advised giving sucralfate 1/2 hr before feedings if possible. If sucralfate has been prescribed to be given every 8 hours, but kittens are being fed more frequently, is it possible, and would it be beneficial, to divide the sucralfate into smaller doses so that it can be given before each feeding? 



    ------------------------------
    MaeLynn Velin
    foster
    Chelsea Bailey Animal Shelter
    MT
    ------------------------------



  • 7.  RE: Webinar: Practical Calicivirus: All You Need to Know from Diagnosis to Adoption - 4/17/24

    Posted 07-02-2024 06:55 AM

    Hi MaeLynn, thanks for this question

    The answer is, I'm not sure. We haven't ever done that before to my knowledge. 

    I think you're asking if it's okay for you take the total mg they would get in a day and just divided it up into smaller, more frequent doses, to correspond with meals. 

    If you're doing it 30min before they eat, and you make sure you aren't going over the total mg they need for the day, it shouldn't hurt anything. We don't know 100% for sure that the sucralfate has a strong effect on mouth ulcers, but we think it might, it appears to help. With that said, we KNOW it has a good effect for esophageal/stomach ulcers. Do calici kittens get esophageal/stomach ulcers? Probably yes to esophageal, probably no to stomach ulcers. 

    So the biggest downside I can think of to breaking the dose down into smaller doses - I think you're going to get less medication swallowed down into the esophagus, or not a high enough dose of medication swallowed down, which means you won't have that protective effect down in the esophagus. It might benefit the mouth though, which might be worth it. 

    If it was me, I would probably try it if you have the staff/bandwidth to dose that frequently and to make sure you're doing it 30min before each meal. And of course make sure you aren't going over the total mg dose for the day. You could test it out on some kitties and see if you see easier force feeding/better results on the kittens getting the more frequent dosing, vs. days when you do it q8h. 

    It's an interesting question! Monica may have tried it and have more info, these are just my thoughts on it. 



    ------------------------------
    Lindsay O'Gan
    Instructional Design Manager
    APA
    TX
    ------------------------------



  • 8.  RE: Webinar: Practical Calicivirus: All You Need to Know from Diagnosis to Adoption - 4/17/24

    Posted 14 days ago

    Hi, 

    I've always thought that Calicivirus flare-ups were related to stress. For example, if a cat has been infected and recovered they may have a flare-up of oral ulcers if they are stressed out at a later date. Is this not the case? 

    Thank you, 

    Bree



    ------------------------------
    Breanna McBride
    Feline Care Specialist
    Fraser Valley Humane Society
    ------------------------------



  • 9.  RE: Webinar: Practical Calicivirus: All You Need to Know from Diagnosis to Adoption - 4/17/24

    Posted 10 days ago
    Hi Bree!

    I haven't found that to be the case in my experience - tongue ulcers I've really only seen in  active infections early on in the disease process. Once those clear up and the kittens are not showing symptoms, they don't tend to have flare ups of calici symptoms later in life. However, it's important to note that there appears to be a link between calicivirus infection and later developing stomatitis. Several studies have shown that cats with Feline chronic gingivostomatitis (FCGS) tend to have higher rates of being chronic calici carriers when compared to control groups. So in that regard, you could hypothetically see ulceration later in life, but in the form of stomatitis, which (in my experience) tends to look a bit different than your traditional calici ulcers which present primarily on the tongue and lips.

    Interesting information about the link between calici and stomatitis: 
    The aetiology of FCGS remains uncertain and several infectious agents can be associated with FCGS. In a prospective study, FCV was more commonly detected by reverse-transcriptase PCR (RT-PCR) in 52 cats with FCGS (54%) than in 50 healthy age-matched control cats (24%) (Belgard et al., 2010). Similar results were found in a study investigating 42 oral biopsies of cats with FCGS (40% FCV RT-PCR-positive versus none of the 19 controls) (Dowers et al., 2010). Additional studies confirmed these observations also in a larger population of cats in Spain (260 cats with FCGS, 59% FCV-positive versus 98 controls, 15% FCV-positive) (Fernandez et al., 2017) and in cats in Japan (Nakanishi et al., 2019). Likewise, using unbiased metagenomic and transcriptomic analyses of 23 cats with FCGS and 19 control cats, the only microbe strongly associated with FCGS was FCV (Fried et al., 2021). However, the FCV RNA loads in FCV-positive cats with FCGS were not associated with disease severity (Druet and Hennet, 2017). In contrast to the majority of published studies, no FCV antigen was found in the FCGS lesions of 26 cats examined by immunohistochemistry (Rolim et al., 2017). An insight into aetiopathogenesis was derived from the analysis of adipose-tissue-derived mesenchymal stem cells (AD-MSC). Secretomes of AD-MSC have anti-inflammatory, immunomodulatory and regenerative capabilities in some viral diseases. MSC from FCV-infected cats with FCGS had increased secretion of pro-inflammatory cytokines (interleukin 6 and 8, keratinocyte chemoattractant and Rantes) and an altered proteome profile compared to MSC from healthy cats (Villatoro et al., 2022). Antiviral effects of AD-MSC were related to in vitro dose-dependent reduction of FCV replication and not inhibition of cell entry (Teshima et al., 2022). 

    --
    Lindsay O'Gan
    Instructional Design Manager





  • 10.  RE: Webinar: Practical Calicivirus: All You Need to Know from Diagnosis to Adoption - 4/17/24

    Posted 14 days ago

    Hi there, 

    I always thought that Calicivirus symptoms could return with stress (in a previously infected but recovered cat). Is this not the case?



    ------------------------------
    Breanna McBride
    Feline Care Specialist
    Fraser Valley Humane Society
    ------------------------------



  • 11.  RE: Webinar: Practical Calicivirus: All You Need to Know from Diagnosis to Adoption - 4/17/24

    Posted 04-17-2024 01:56 PM

    This question was asked in the comments section but we didn't see it until after the webinar was over, so I wanted to address it here: 

    From Carol Walker: Somewhere about 17 minutes in, you had something that was given with fluids, but the amount was hard to understand  if you were talking about the medication or the fluids ?
    When I'm giving oral medications, a lot of times I'll combine them all in one syringe if possible (crush up tablets and add to the liquid) so that I just have to give them 1 syringe of medicine. This can help minimize pain/drooling. I wouldn't do this with oral buprenex probably since it is absorbed more sublingually and it's such a small dose.  

    Monica mentioned that sometimes when she is treating and giving SQ fluids, she'll add Vit B12 injectable to the LRS SQ. At APA! it isn't currently part of our treatment protocol, but it is something we use in neonatal kittens for various conditions (like diarrhea), and we give it at 0.1cc per pound (450g) mixed into the SQ fluids. 
    I hope that helps!


    ------------------------------
    Lindsay O'Gan
    Instructional Design Manager
    APA
    TX
    ------------------------------