Thanks, Dr. Aziz!
Original Message:
Sent: 12-22-2025 10:49 AM
From: Chumkee Aziz
Subject: Community Conversations - 12/15/2025 - New Insights in Parvo Care
Info about: full USDA approval of CPMA and questions regarding thawing and refreezing CPMA:
First, CPMA also now has full USDA approval and a new brand name: Trutect (anivovetmab).
Second, I checked in with an Elanco vet re: the thawing / refreezing question for CPMA and wanted to share their written response below:
- Proper storage of CPMA is in a deep freezer or within the freezer box in a freezer portion of a fridge / freezer combination unit.
- To help with conversations where a customer has inadvertently stored a CPMA carton in a freezer (non-deep freezer) without the freezer box, there is a little more information:
- CPMA has undergone freeze / thaw testing. This includes placing the product at ambient temperature for 20 minutes then refreezing. This was repeated 10 times with no impact to product potency noted.
- Reminder that regular freezers (not deep freezers) undergo freeze / thaw cycles throughout the day resulting in CPMA storage temperature to be out of guidelines. Every freezer has a different frequency of freeze / thaw cycles it undergoes, but in general it's 2-3 freeze / thaw cycles a day.
- Reminder – freeze / thaw testing gives us information about product potency and does not include administering the product to animals. While we can make conclusions regarding potency with this data, we can't speak to the safety or efficacy of improperly stored product. That will be at the veterinarian's discretion if they want to utilize improperly stored product.
What it means in practice:
CPMA seems quite stable with repeated, short thaw/refreezing. Studies did not show loss of potency after 10 cycles of thaw/refreezing. The company is not relaxing the labeled storage reqs, though, bc typical clinic freezers fluctuate 2–3 times per day and that pattern is variable, so it is still considered off‑label storage.
The thaw/refreezing data only speak to potency, not to clinical safety or efficacy, so Elanco will not technically tell us that "improperly stored" product is safe or effective (though it is likely still potent); if a vial has been stored outside guidelines, veterinary discretion should be used to determine if the vial should be used or discarded.
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Chumkee Aziz, DVM, DABVP (Shelter Medicine Practice)
Outreach Veterinarian
UC Davis
Original Message:
Sent: 12-09-2025 09:44 AM
From: Sheila Kouhkan
Subject: Community Conversations - 12/15/2025 - New Insights in Parvo Care
Updated 12/15/25 at 1:12 pm - Recording now available to watch on-demand!
Enter here for a chance to win the December Community Conversations giveaway after watching live or on-demand.
Please note: All views expressed on these calls are not necessarily endorsed by Maddie's Fund.
We hope to see you on the next Maddie's Community Conversation on Monday, December 15, 2025 at 11am PT / 2pm ET for "New Insights in Parvo Care" a conversation with Drs. @Chumkee Aziz, @Lucy Fuller, and @Biana Tamimi.
This panel discussion will examine the use of Elanco's Canine Parvovirus Monoclonal Antibody (CPMA) therapy in animal shelter settings, featuring insights from veterinarians who have implemented CPMA on the ground in cats and dogs. Panelists will discuss the practical considerations, including resource allocation, staff training, and the impact of CPMA on high-risk populations. They will share real-world experiences with treatment protocols, decision-making around patient selection, and how CPMA fits into broader parvovirus management strategies. The session will emphasize key outcomes, lessons learned, and practical recommendations to support shelters considering this therapy.
This session is especially relevant for adoptions and foster staff & volunteers, veterinary professionals (vets, techs, support staff), and behavior staff & volunteers - but all are welcome!
🔑 Key Takeaways:
- CPMA has the potential to shorten the treatment duration, which is especially valuable for the behavioral wellbeing of young animals.
- Early recognition of parvovirus is essential for initiating CPMA therapy promptly, which may lead to improved outcomes.
- Effective use of CPMA in shelters depends on clear protocols for patient selection, staff training, and workflow integration.
- Using CPMA has shown a reduced shedding period in dogs infected with parvovirus, which ultimately ha shortened their length of stay.
- Case selection is important - this is not a miracle drug.
Don't forget! $10,000 in grants each month! Maddie's Fund will be giving away up to $10,000 in grants each month! You can enter for a chance to win each time you attend a call or watch it on demand during the month by completing the monthly giveaway drawing entry form.
Register for Community Conversations hosted via Zoom.
🧠 Got Topic or Speaker Suggestions?
We want to hear your ideas! If there's a topic you're curious about or a speaker you'd love to hear from, please share your suggestions with us on our Community Conversations Suggestions thread.
Looking forward to being in community with you!
#EducationandTraining
#Medicine,SurgeryandSterilization
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Sheila Kouhkan
Senior Education Specialist
Maddie's Fund
CA
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