Animal Welfare Professionals

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  • 1.  Intranasal Vaccinations to kittens?

    Posted 03-23-2023 01:45 PM

    Hello, I'm new to the group, so please excuse the question if it has been discussed previously.  My name is Ronnie DeForrest, DVM, and I am the veterinarian for McMinn Regional Humane Society in Athens, TN.  We had a particularly rough season last season with URIs in kittens.  We currently give FVRCP parenterally on intake, however, I attended a CE video presentation recently, and I'm pretty sure the presenter said intranasal vaccines provide protection faster because of mucosal contact. (I can't remember the presenter)   Intranasal vaccines are labeled by manufacturer for 12 week or  older healthy kittens/cats.   I can't get the vaccine manufacturer to commit to whether it is safe or effective to give to young kittens. 

    Does anyone have experience or feedback?  I'm just curious if IN vaccines would be advantageous.

    Thanks


    #AdmissionsandIntake(includingIntake-to-placement)

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    Ronnie DeForrest
    Veterinarian
    McMinn Regional Humane Society
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  • 2.  RE: Intranasal Vaccinations to kittens?

    Posted 03-24-2023 06:50 AM

    Hi Ronnie! 

    I'm now following your thread because I actually have a different slant on your question: we've been thinking about shelter use of the intranasal vaccine as a treatment for those with "chronic" URI - those that seem to keep relapsing, or have had symptoms for 3 weeks. That vaccine would just be the FVRC, without the panleukopenia portion. 

    So I'm also wondering how many people have used the intranasal vaccine, and what kind of results they did or did not see! 

    https://pubmed.ncbi.nlm.nih.gov/26269455/

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    Kirsten Cianci
    Palmetto Animal League
    Ridgeland, SC 29936
    =^..^=
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  • 3.  RE: Intranasal Vaccinations to kittens?

    Posted 03-24-2023 07:54 AM

    Hi Kristen - 

    I talked to Dr Lappin about this research at Western States a couple years ago. I have tried it in rescue and have seen less than 50% of chronic URI resolve, mostly in kittens to be honest.  It has worked better in cats affected for less time. However, our long time chronic URI did not resolve and inflammation associated with dental disease/stomatitis did not improve. We found the greatest improvement with preventing the chronic status from occuring by using nasal vaccines at intake. During that conversation he also talked about using doxycycline in these cats and I have found that to be most helpful in the long time chronic URI cats. Hope that helps! 



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    Samantha Brown
    President/Founder
    Living the Dream Rescue
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  • 4.  RE: Intranasal Vaccinations to kittens?

    Posted 03-24-2023 08:12 AM

    Hi Samantha:
    That is really interesting information. I hope you don't mind a few more questions!

    *Intranasal vaccine at intake: any specific age? Or all kittens' first vaccine regardless? We have a lot of kittens that go out into foster. In that case, would you use the parenteral vaccine first, and then the intranasal when they come back to the shelter to stay?

    *Doxycycline - at the first sign of a bacterial component to URI? That tends to be our first-line antibiotic when we get to that point, and I'm wondering if we're just stopping meds too soon. Did Dr. Lappin recommend a specific duration of therapy that then seemed to make a difference long-term? And doxy for your long-term URI cats - again, how long did you treat? 

    *P.S. Full disclosure: When I was in private practice, I used to stalk Dr. Lappin lectures every chance I got! :)



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    Kirsten Cianci
    Palmetto Animal League
    Ridgeland, SC 29936
    =^..^=
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  • 5.  RE: Intranasal Vaccinations to kittens?

    Posted 03-24-2023 11:14 AM

    HI Kristen - 

    I don't mind at all! 

    We implemented Nasal vaccines in our bottle baby nurseries at a few shelters in AZ a few years ago, starting at about 2 weeks and continuing every 2 weeks until we begin their official parenteral kitten series at 6 weeks. We initially did this to prevent panleuk after we lost our entire nursery a few times. It worked so well and we also saw a huge decrease in URI incidence. We began giving every cat a nasal on intake last year and have noticed a significant increase in the continued/sustained health and a decrease in length of stay.  Generally our intake vaccine is nasal, boosters are parenteral. I am a huge fan! We are all foster based so they come to a medical intake appointment initially and then come back every 3-4 weeks for vaccines. Our neonate fosters have extra nasal vaccines on hand to give them every 2 weeks. 

    RE: Doxycycline - for chronic we do at least 3 weeks if signs of bacterial component and continue 1 week past cessation of symptoms. I've had a few that responded pretty quickly and have had a few others that I did 4-5 weeks on. One of my long time fosters got 5 weeks and has never relapsed. She had some nasal turbinate damage so still has loud nasal sounds but no discharge. She received the treatment 2 years into her chronic status and that was two years ago. We had tried everything else but had not tried long duration.

    I absolutely agree! I am a fan girl myself! I go to all of his lectures! I used to read his papers and Dr Pedersens when I was a kid! I appreciate their contributions to cat medicine so much! 



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    Samantha Brown
    President/Founder
    Living the Dream Rescue
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  • 6.  RE: Intranasal Vaccinations to kittens?

    Posted 03-24-2023 07:46 AM

    HI Dr DeForrest - 

    Vet student here that has worked in Non profit for almost 20 years. We implemented Nasal vaccines in our bottle baby nurseries at a few shelters in AZ a few years ago, starting at about 2 weeks and continuing every 2 weeks until we begin their official parenteral kitten series at 6 weeks. We initially did this to prevent panleuk after we lost our entire nursery a few times. It worked so well and we also saw a huge decrease in URI incidence. We began giving every cat a nasal on intake last year and have noticed a significant increase in the continued/sustained health and a decrease in length of stay.  Generally our intake vaccine is nasal, boosters are parenteral. I am a huge fan! There have also been reports of less kidney disease in cats that have received nasal vaccines over injectable. Happy to discuss more if you would like! 



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    SAMANTHA BROWN
    President/Founder
    Living the Dream Rescue
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