I'm confused by your reply...toltrazuril is not an OTC product and requires veterinary prescription just like ponazuril does.
Compounded ponazuril suspension is considered fairly stable (unlike, for example, doxycycline suspension). All compounded medications carry a maximum expiration date of 6 months from time of compounding, primarily due to not-as-stringent manufacturing, QC, and stability testing when compared to FDA-approved formulations.
Use of a coccidiostat as a preventative at time of intake is generally accepted practice (we do that). In my reply, I meant that I would not recommend ongoing preventative doses after treatment. If the environment and animals (bathed) are appropriately cleaned and disinfected, and facilities maintain good biosecurity and housing standards there should not be ongoing exposure after treatment.
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Rachel Powell DVM
Director of Surgery
Greenhill Humane Society
Eugene, OR
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Original Message:
Sent: 11-20-2024 09:05 PM
From: Sharyn Berg
Subject: Toltrazuril use in Cats
1. All the documentation I find says that it is a very forgiving medication and there are no major negatives side effects. Has anyone experienced any? No. But ponazuril is more effective than toltrazuril and is the recommended treatment.
Except Toltrazuril is OTC and Ponazuril is Rx, expensive and expires quickly if compounded. If not compounded, it has very hit and miss availability. Little rescues gotta do what little rescues can do.
2. Are people using Toltrazuril as a preventative? At what frequency and what dose? I've considered putting them on Albon as a preventative once they have solid poops, do you think that would help? I would not use any medication as a "preventative".
My understanding it was being used on kitties as a preventative protocol on intake and Toltrazuril worked better as a preventative, rather than a cure. Ponzauril works better once infection has happened, but see answer above.
bad poops are such a PITA to all!
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Sharyn Berg
Animal Allies Florida
Original Message:
Sent: 11-20-2024 02:57 PM
From: Rachel Powell
Subject: Toltrazuril use in Cats
I should add...stick with Rescue...BUT use it at 1:16 dilution (8oz/gallon). And remember that mechanical removal of oocysts through cleaning with a detergent is at least as is important as disinfecting. That's why Rescue is such a good option as it's a one-step product for cleaning and disinfection. There are very real environmental hazard concerns with ammonia or bleach. Certainly, those products should not be used as long as kittens are still housed in the ward.
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Rachel Powell DVM
Director of Surgery
Greenhill Humane Society
Eugene, OR
Original Message:
Sent: 11-20-2024 09:24 AM
From: Rachel Powell
Subject: Toltrazuril use in Cats
Hi! Experienced shelter vet here. Coccidia can be super-frustrating to treat so I feel your pain. Answers to your questions below:
- All the documentation I find says that it is a very forgiving medication and there are no major negatives side effects. Has anyone experienced any? No. But ponazuril is more effective than toltrazuril and is the recommended treatment.
- Once we get it cleared, it is shortly reappearing. Are people using Toltrazuril as a preventative? At what frequency and what dose? I've considered putting them on Albon as a preventative once they have solid poops, do you think that would help? I would not use any medication as a "preventative". Reinfection is very common. Make sure to be thoroughly cleaning or discarding bedding. Consider bathing the kittens after treatment to remove spores.
- I am so sick of it! And it's so dangerous to the little kittens. Yes!
- Any opinions if Rescue is a good cleaning agent for it or do I need to use bleach? Rescue is highly effective and works in the presence of organic material (bleach does not) and is safer for the kittens. Stick with Rescue!
- Thank you for your feedback.
Let me know if you have any other questions!
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Rachel Powell DVM
Director of Surgery
Greenhill Humane Society
Eugene, OR
Original Message:
Sent: 11-19-2024 10:39 AM
From: Michelle DePrima
Subject: Toltrazuril use in Cats
We have used 5% Toltrazuril to treat Coccidia for years. The last 2 years, we have struggled with getting it under control. We are a foster network and honestly, I think we need to reduce the number of kittens in each foster home. We are working on it.
Until we can achieve that, I have some questions...
- All the documentation I find says that it is a very forgiving medication and there are no major negatives side effects. Has anyone experienced any?
- Once we get it cleared, it is shortly reappearing. Are people using Toltrazuril as a preventative? At what frequency and what dose? I've considered putting them on Albon as a preventative once they have solid poops, do you think that would help?
- I am so sick of it! And it's so dangerous to the little kittens.
- Any opinions if Rescue is a good cleaning agent for it or do I need to use bleach?
- Thank you for your feedback.
#Medicine,SurgeryandSterilization
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Michelle DePrima, Director/Medical Director
Cats Pawjamas Rescue Society
Olathe KS
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